KNOW YOUR LUNGS:  November is Alpha Awareness Month. Have you heard of Alpha-1 Antitrypsin Deficiency (Alpha-1)? Alpha-1 is an inherited genetic condition that can affect the lungs and liver. Many people have never heard of it, yet early diagnosis can make an important difference in the lives of those affected by this disorder.

💙 Alpha-1 occurs when the body doesn’t produce enough of a protective protein called alpha-1 antitrypsin (AAT). This protein helps protect lung tissue from inflammation and damage. 🫁 How is it connected to bronchiectasis?

• Alpha-1 can contribute to lung damage.

• Some people with Alpha-1 develop bronchiectasis.

• Damaged airways can make it harder to clear mucus, increasing the risk of recurring respiratory infections.

🔎 Common symptoms may include:

•            Shortness of breath

•            Chronic cough

•            Excess mucus or sputum

•            Recurrent respiratory infections

•            Wheezing and fatigue

🧬 Why does testing matter?  Alpha-1 can go undiagnosed for years because its symptoms often resemble asthma, COPD, or other respiratory conditions. Current guidelines recommend that people with COPD and unexplained bronchiectasis be evaluated for Alpha-1.

💡 What can you do?

✔️ Ask your pulmonologist whether Alpha-1 testing is appropriate.

✔️ Know your family history.

✔️ Avoid smoking and secondhand smoke.

✔️ Stay current with recommended vaccinations.

✔️ Work with your pulmonary team on an individualized airway-clearance plan.

💙 AWARENESS MATTERS! Not every person with bronchiectasis has Alpha-1, and not everyone with Alpha-1 develops bronchiectasis. But understanding the connection may help identify an underlying cause and guide treatment.

Alpha-1 Foundation – Contact Information  : Phone: 1-877-228-7321   Alternative phone: 305-567-9888

Website:  https://alpha1.org/alpha-1-awareness-month/

Helpful Resources-the Foundation can help with:

•            Patient education and educational materials.

•            Alpha-1 testing information.

•            Patient support groups.

•            Finding physicians who specialize in Alpha-1.

•            Research and clinical trial information.

Have you or someone you know been tested for Alpha-1? Let’s start the conversation.