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Rifampin and Azithro RX -any suggestions on diet & timing?

In: Treatments & Medications
2 153
PJ

Hello,

I will be starting Rifampin and Azithro, but chose not to add the Amikacin at this point. (they only offered the IV and am concerned about the side effects and it makes it very difficult to work full time and get to the hospital for the IV infusion 3x week). 

Should I be taking a probiotics as well to help maintain healthy gut bacteria?

Is there a suggested schedule of when/how to take the meds + probiotic? 

Any other foods I should increase or remove from my diet to help? (I do not drink alcholol and do not take other meds other than daily vitamins).


I appreciate any help or feedback as this is a bit scary to do.


Thank you,

Patricia

Latest Activity: September 17, 2026
2 Replies

Replies

K

Patricia,

Hello! I am sure that it is a "little scary," to say the least, to take these antibiotics for an extended period.

Rifampin is best taken at night, 1-2 hours before you go to bed. Rifampin will discolor your urine to an orange color. Rifampin has many drug interactions, so make sure that your supplements are reviewed by your doctor or pharmacist.  I am glad that you don't drink alcohol since this is one drug that absolutely does not mix well with any alcohol.

Azithromycin can be taken with or without food- I always prefer to take it with food. Discuss any antacids you may be taking with your pharmacist while taking this antibiotic.

Yes, it is recommended to take probiotics, but not within a 2-hour timeframe of taking your antibiotics.  Do you have access to a registered dietitian to assist you on your journey?  Dietitians are covered by some insurance plans. I assume that your healthcare provider informed you that you will need regular lab work while on these drugs.  I hope that the initiation of taking these drugs goes smoothly. Please check in to let us know how you are doing. 

Latest Activity: September 16, 2026

Comments

PJ

Thank you! Yes, I will have regular labs along the way. I appreciate the feedback & will look into a nutritionist. 

Latest Activity: September 17, 2026
K

Patricia,

You are most welcome! I have been down the road that you are now traveling. Please reach out at anytime with any questions you may have. 

Latest Activity: September 17, 2026
PJ

I do have a question, if I may :) how do I find a nutrionist? i am looking both on the Northwestern Medicine website (my doctors are in this medical group) and in my insurance. The nutrionists that come up are MD's specializing in Pediatrics, Diabetes, or other Gastroenterology conditions and that doesn't seem to be what I'd be looking for. Any help on how to find the right type of nutritionist would be great! 

Latest Activity: September 17, 2026
K

Patricia,     Great question- you want a personal referral from your Pulmonologist, gastroenterologist if possible. You want a registered dietitian who truly understands the needs of an NTM patient. It may take sometime to find someone in your area but it is certainly worth the time and effort to find the right person. I wish that I had found the right dietitian early on in my diagnosis. Preventative measures are far easier to deal with than curative measures. Have you watched any of the videos on Nutrition by Michelle MacDonald? https://m.youtube.com/watch?v=30L2Ha4W_Nk&ra=m

Latest Activity: September 17, 2026
D

I hope you're able to get access to a nutritionist. If not, even asking your doctor some of these questions might help. Sending well wishes!

Latest Activity: September 17, 2026

Comments

PJ

Thank you Delia!

Latest Activity: September 17, 2026

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